Report generated at: 04/29/2021 02:07 PM PDT

CP Figure

CP indiv muts

CP combo muts

VP Figure

VP indiv muts

VP combo muts

Plasmas Figure

CP and VP summary

DMS

DMS vs fold

DMS vs fold 3D

DMS vs fold by mab

DMS Statistic Test

All

## Warning in chisq.test(tbl): Chi-squared approximation may be incorrect
## 
##  Pearson's Chi-squared test
## 
## data:  tbl
## X-squared = 15733, df = 8690, p-value < 2.2e-16
## 
##  Spearman's rank correlation rho
## 
## data:  df$fold and df$score
## S = 3106546, p-value < 2.2e-16
## alternative hypothesis: true rho is not equal to 0
## sample estimates:
##       rho 
## 0.5726296

Fold >= 10 and score >= 0.1

## Warning in chisq.test(tbl): Chi-squared approximation may be incorrect
## 
##  Pearson's Chi-squared test
## 
## data:  tbl
## X-squared = 1834.8, df = 1748, p-value = 0.07276
## 
##  Spearman's rank correlation rho
## 
## data:  df_Fold_gt10$fold and df_Fold_gt10$score
## S = 25237, p-value = 0.008798
## alternative hypothesis: true rho is not equal to 0
## sample estimates:
##       rho 
## 0.3326979

Fold >= 10

## Warning in chisq.test(tbl): Chi-squared approximation may be incorrect
## 
##  Pearson's Chi-squared test
## 
## data:  tbl
## X-squared = 3084.4, df = 3132, p-value = 0.7246
## 
##  Spearman's rank correlation rho
## 
## data:  df_Fold_gt10$fold and df_Fold_gt10$score
## S = 33432, p-value = 5.498e-10
## alternative hypothesis: true rho is not equal to 0
## sample estimates:
##       rho 
## 0.6224954

Fold < 10

## Warning in chisq.test(tbl): Chi-squared approximation may be incorrect
## 
##  Pearson's Chi-squared test
## 
## data:  tbl
## X-squared = 2952.6, df = 1530, p-value < 2.2e-16
## 
##  Spearman's rank correlation rho
## 
## data:  df_Fold_lt10$fold and df_Fold_lt10$score
## S = 2584307, p-value = 0.0002473
## alternative hypothesis: true rho is not equal to 0
## sample estimates:
##       rho 
## 0.2208996

Fold >10 and score < 0.1

## Warning in chisq.test(tbl): Chi-squared approximation may be incorrect
## 
##  Pearson's Chi-squared test
## 
## data:  tbl
## X-squared = 140, df = 133, p-value = 0.3218
## 
##  Spearman's rank correlation rho
## 
## data:  df_Score_outlier$fold and df_Score_outlier$score
## S = 860.58, p-value = 0.1269
## alternative hypothesis: true rho is not equal to 0
## sample estimates:
##       rho 
## 0.3529458

Mab, Score

## Warning in chisq.test(tbl): Chi-squared approximation may be incorrect
## 
##  Pearson's Chi-squared test
## 
## data:  tbl
## X-squared = 3001.1, df = 1580, p-value < 2.2e-16